Targeted Protein Degradation: A New Pharmacology Paradigm?
Targeted Protein Degradation: A New Pharmacology Paradigm? Traditional drug development focuses on targeting proteins with a defined binding pocket or active site to regulate protein activity. These strategies have exploited only around 400 of the 4000 disease-associated proteins 1, which means 90% of disease-associated proteins, including many high priority targets, currently remain ‘undruggable’ 2. However, a new […]
Augmenting Drug Discovery with Artificial Intelligence
Augmenting Drug Discovery With Artificial Intelligence Artificial intelligence (AI) is profoundly impacting drug discovery, a critical area in the biotech industry. Developing new drugs is a time-consuming and expensive process, often involving trial and error. Moreover, low-hanging fruits in this field are all gone, meaning researching new medicines has become even more challenging and pricy. […]