Drug-Drug Interactions
Drug-Drug Interactions
In the drug discovery process, understanding potential compound associations with transporters in the beginning period of improvement is basic for choosing candidates with alluring drug metabolism and security profiles. Acubiosys gives broad carrier and permeability testing services, state-of-the-art equipment, and logical expertise in DMPK to help your particular needs. We plan and actualize Drug-Drug Interaction (DDI) studies to give information that our customers use in their lead selection and streamlining forms and administrative entries. Our strategies conform to administrative rules including the FDA Draft Guidance distributed in 2017, In Vitro Drug Metabolism-and Transporter-Mediated Drug-Drug Interaction Studies. Our extensive services include:
Our Research
- CYP450 inhibition
- Time-dependent inhibition(Single point)
- Time-dependent inhibition (IC50 shift)
- CYP P450 and UGT reaction Phenotyping
- CYP Inhibition
- UGT Inhibition